Hsieh M L, Quint L E, Faust J M, Turner J E
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109.
Magn Reson Imaging. 1993;11(4):599-601. doi: 10.1016/0730-725x(93)90480-2.
We report a case of an enhancing middle mediastinal mass imaged by MR and CT. Repeated nondiagnostic biopsies in this 25-yr-old male patient had resulted in profuse hemorrhage. Final pathological diagnosis after thoracotomy and debulking was Castleman disease. This is a rare, benign lymphoproliferative disorder of uncertain etiology. Histological varieties include the hyaline vascular type (80-90%) and the plasma cell type (10-20%). Cure is generally accomplished via surgical excision. This entity should be included in the differential diagnosis of enhancing mediastinal lesions, prompting awareness of the potential for bleeding complications following biopsy.
我们报告一例通过磁共振成像（MR）和计算机断层扫描（CT）成像的中纵隔强化肿块病例。该25岁男性患者多次活检未能明确诊断，导致大量出血。开胸手术及肿瘤减积术后的最终病理诊断为Castleman病。这是一种病因不明的罕见良性淋巴增生性疾病。组织学类型包括透明血管型（80 - 90%）和浆细胞型（10 - 20%）。一般通过手术切除实现治愈。该疾病应列入纵隔强化病变的鉴别诊断，促使人们意识到活检后出血并发症的可能性。
