Johnson J, Tucker H M
Arch Otolaryngol. 1977 Jan;103(1):22-5. doi: 10.1001/archotol.1977.00780180060005.
Amelioration of facial nerve dysfunction has been variably successful and often has resulted in only gross motion. An experimental model has been developed whereby the nerve-muscle pedicle technique used to reinnervate the larynx has been modified to achieve selective reinnervation of paralyzed facial muscles. A series of rabbits underwent facial denervation, following which a nerve-muscle pedicle was transposed to the denervated zygomaticus muscle to achieve selective reinnervation. Subsequent follow-up showed good clinical evidence of reinnervation one to four weeks postoperatively. This was confirmed by electromyographic and histologic findings. It is suggested that the nerve-muscle technique that has been used to correct laryngeal paralysis also may be applied to the selective reinnervation of paralyzed facial muscles.
面神经功能障碍的改善效果不一,通常仅能实现粗略的运动。已开发出一种实验模型,据此对用于喉再支配的神经 - 肌肉蒂技术进行了改良,以实现对麻痹面部肌肉的选择性再支配。一系列兔子接受了面部去神经支配,随后将神经 - 肌肉蒂转移至去神经支配的颧肌以实现选择性再支配。后续随访显示术后1至4周有良好的再支配临床证据。这通过肌电图和组织学检查结果得到了证实。有人提出,用于纠正喉麻痹的神经 - 肌肉技术也可应用于麻痹面部肌肉的选择性再支配。