Christiansen O B, Mathiesen O, Lauritsen J G, Grunnet N
Gynaekologisk obstetrisk afdeling og klinisk immunologisk afdeling, Aalborg Sygehus.
Ugeskr Laeger. 1993 Jun 7;155(23):1802-4.
Information on the birth weight and gestational age at birth was obtained for 79 singleborn women with recurrent miscarriages, 60 of their male partners and, 474 female and 360 male controls. The mean birth weight of the women with recurrent miscarriages was 3265 g which was significantly lower than in female controls (p < 0.025). Of the women in the study group, 10.8% were born preterm compared with 2.9% of the controls (p = 0.01). The mean birth weight of the male partners in the study group did not differ significantly from that of the male controls. It is concluded that there is evidence for a reduced birth weight trait associated with recurrent miscarriages; the trait being manifests itself only in the woman.
研究获取了79名单胎复发性流产女性、她们的60名男性伴侣以及474名女性对照和360名男性对照的出生体重及出生时的孕周信息。复发性流产女性的平均出生体重为3265克,显著低于女性对照(p < 0.025)。研究组中的女性有10.8%为早产,而对照组为2.9%(p = 0.01)。研究组男性伴侣的平均出生体重与男性对照无显著差异。结论是,有证据表明复发性流产与出生体重降低特征有关;该特征仅在女性中表现出来。