Cintin C, Joffe P
Medicinsk nefrologisk afdeling, Københavns Amts Sygehus i Herlev.
Ugeskr Laeger. 1993 Jun 21;155(25):1972-3.
Nephrogenic ascites is a clinical diagnosis defined as persistent ascites in a uraemic patient without evidence of a causative specific underlying disease. Contributing mechanisms may include peritoneal membrane changes, fluid overload, hyperparathyroidism, reduced lymphatic drainage, heart failure and hypoproteinemia. A specific treatment has not yet been found. Rigid fluid control, intensive haemodialysis, high-protein diet, intravenous albumin infusion, intraperitoneal steroid injections and paracenteses as well as implantation of a peritoneoatrial pump were all found to be ineffective. Use of peritoneal dialysis has been shown to resolve ascites, but the only effective treatment is renal transplantation, as demonstrated in the case-report.
肾源性腹水是一种临床诊断，定义为尿毒症患者出现持续性腹水，且无明确病因的特定基础疾病证据。其促成机制可能包括腹膜改变、液体超负荷、甲状旁腺功能亢进、淋巴引流减少、心力衰竭和低蛋白血症。目前尚未找到特异性治疗方法。严格的液体控制、强化血液透析、高蛋白饮食、静脉输注白蛋白、腹腔内注射类固醇、腹腔穿刺放液以及植入腹膜-心房泵均被证明无效。腹膜透析已被证明可消除腹水，但如病例报告所示，唯一有效的治疗方法是肾移植。
