Goodnight S H, Coull B M, McAnulty J H, Taylor L M
Department of Pathology, Oregon Health Sciences University School of Medicine, Portland 97201-3098.
West J Med. 1993 Apr;158(4):385-92.
We summarize current information about aspirin and other antiplatelet drugs in patients with cardiac and vascular disease. For each indication, we briefly summarize the rationale for the use of antiplatelet therapy and describe the findings of relevant clinical trials. We propose recommendations for the use of these agents in clinical practice. Part I covers the use of antiplatelet therapy for the primary and secondary prevention of myocardial infarction, coronary thrombolysis, unstable and chronic stable angina, and coronary artery-saphenous vein bypass grafts. In part II we review the use of antiplatelet agents in coronary angioplasty, atrial fibrillation, artificial cardiac valves, stroke, and peripheral vascular disease.
我们总结了目前关于心脏和血管疾病患者使用阿司匹林及其他抗血小板药物的信息。对于每种适应症，我们简要总结了使用抗血小板治疗的理论依据，并描述了相关临床试验的结果。我们提出了在临床实践中使用这些药物的建议。第一部分涵盖了抗血小板治疗在心肌梗死的一级和二级预防、冠状动脉溶栓、不稳定型和慢性稳定型心绞痛以及冠状动脉-隐静脉旁路移植术中的应用。在第二部分中，我们回顾了抗血小板药物在冠状动脉血管成形术、心房颤动、人工心脏瓣膜、中风和外周血管疾病中的应用。
