Kaliuzhnyĭ L V, Litvinova S V, Inozemtsev A N, Kaliuzhnyĭ A L, Aristova V V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Mar-Apr;43(2):371-6.
Preliminary neurotropin administration improved subsequent conditioned avoidance learning of rats in a shuttle-box: increased the number of conditioned avoidance reactions and decreased their latency in comparison with the control but did not change the number of intertrial responses. "The demolition" (5 series of negative reinforcements applied despite of avoidance occurrence) caused behavioural stress reactions and inhibited the conditioned and unconditioned avoidance learned reactions. Neurotropin injection before the demolition abolished such disturbances, that having been done after the demolition restored conditioned avoidance. The positive effects of neurotropin were suggested to be due to its antistress property and ability to improve the formation of a result of an acceptor of action.
与对照组相比，增加了条件性回避反应的次数并缩短了其潜伏期，但未改变试验间反应的次数。“破坏”（尽管出现回避仍施加5组负强化）引发行为应激反应，并抑制条件性和非条件性回避学习反应。在“破坏”前注射神经妥乐平可消除此类干扰，在“破坏”后注射则可恢复条件性回避。神经妥乐平的积极作用被认为归因于其抗应激特性以及改善作用受体结果形成的能力。
