Poirrier R
Centre Hospitalier Universitaire du Sart Tilman, Liège, Belgique.
Acta Otorhinolaryngol Belg. 1993;47(2):167-81.
Snoring and excessive sleepiness are the hallmarks of obstructive sleep apnea syndrome but other clinical manifestations are present and a precise assessment of the disease involves clear definitions of the various kinds of apnea. Several pathogenetic factors (functional, anatomical, neurological, genetical) are still being discussed. However new insights of the pathophysiology of apneas allow more reliable treatments. Central nervous and cardiovascular complications as well as the traumatic morbidity, associated with excessive daytime sleepiness, make it a major public health problem.
打鼾和过度嗜睡是阻塞性睡眠呼吸暂停综合征的标志,但还存在其他临床表现,对该疾病的精确评估涉及对各种呼吸暂停的明确定义。几种致病因素(功能、解剖、神经、遗传)仍在讨论中。然而,对呼吸暂停病理生理学的新见解使治疗更可靠。中枢神经和心血管并发症以及与日间过度嗜睡相关的创伤性发病率,使其成为一个重大的公共卫生问题。