Nisen H O, Saarinen O, Ruutu M L, Edgren J
Fourth Department of Surgery, Helsinki University Central Hospital, Finland.
Acta Radiol. 1993 Jul;34(4):335-8.
The aim of this study was to find out the normal response of the duplex Doppler (DD) parameter resistance index (RI) during a high dose prostaglandin E1 (40 micrograms) induced erection and to evaluate the clinical usefulness of DD scanning in the diagnosis of cavernovenous leakage (CVL). The results of DD scanning and cavernometry were compared in 10 potent control subjects and 82 impotent patients RI was > or = 1 in all control subjects later than 10 min after the intracavernous injection and RI at 20 min after the injection (RI20) was chosen as a clinical parameter. An inverse correlation (r = -0.69, p < 0.001) between RI20 and the maintenance flow (MF) at 150 mm Hg (MF150) was demonstrated. Sensitivity and specificity of RI20 (values < 1 indicating CVL) as a test of CVL (MF150 > 18 ml/min) were 89% and 86%, respectively. In conclusion, the measurement of RI20 in DD scanning after an adequate pharmaco-stimulation is a reliable, noninvasive method in the diagnosis of CVL.
本研究的目的是找出在高剂量前列腺素E1（40微克）诱发勃起过程中双功多普勒（DD）参数阻力指数（RI）的正常反应，并评估DD扫描在诊断海绵体漏（CVL）中的临床实用性。对10名性功能正常的对照者和82名阳痿患者进行了DD扫描和海绵体测压结果的比较。所有对照者在海绵体内注射后10分钟后RI≥1，并将注射后20分钟时的RI（RI20）作为临床参数。结果显示RI20与150毫米汞柱时的维持流量（MF）（MF150）之间呈负相关（r = -0.69，p < 0.001）。RI20（值<1表明存在CVL）作为CVL（MF150>18毫升/分钟）检测指标的敏感性和特异性分别为89%和86%。总之，在充分的药物刺激后进行DD扫描测量RI20是诊断CVL的一种可靠的非侵入性方法。
