Oshima M, Yoshida J, Wakabayashi T, Ito K, Tadokoro M, Kato T, Sakuma S
Department of Radiology, Nagoya First Red Cross Hospital, Japan.
Ann Nucl Med. 1993 May;7(2):119-22. doi: 10.1007/BF03164577.
A 45-year-old man with suspected recurrent malignant glioma was evaluated by magnetic resonance imaging (MRI), positron emission tomography (PET) and 131I labeled monoclonal antibody G-22 (G-22) scan. Following Gadolinium-DTPA, a TI-weighted spin echo image (TR 500 msec, TE 20 msec) demonstrated a large mass with an irregular margin in the left temporo-parietal area. An 18F labeled fluorodeoxyglucose PET study demonstrated marked accumulations in the left temporo-parietal area. Serial 131I-G-22 scintigraphy was obtained for a week after the injection. The uptake was most increased on the 2nd day after the injection. 131I G-22 was specific for tumor-associated antigens.
一名疑似复发性恶性胶质瘤的45岁男性接受了磁共振成像（MRI）、正电子发射断层扫描（PET）和131I标记单克隆抗体G-22（G-22）扫描评估。静脉注射钆喷酸葡胺后，T1加权自旋回波图像（重复时间500毫秒，回波时间20毫秒）显示左颞顶叶区域有一个边界不规则的大肿块。18F标记的氟脱氧葡萄糖PET研究显示左颞顶叶区域有明显的放射性聚集。注射后一周内进行了连续的131I-G-22闪烁扫描。注射后第2天摄取增加最为明显。131I G-22对肿瘤相关抗原有特异性。
