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人体氧化应激状态的测量。

Measurement of oxidative stress status in humans.

作者信息

Pryor W A

机构信息

Biodynamics Institute, Louisiana State University, Baton Rouge 70803.

出版信息

Cancer Epidemiol Biomarkers Prev. 1993 May-Jun;2(3):289-92.

PMID:8318882
Abstract

The oxygen atmosphere under which we live produces a continuing barrage of oxidative damage to all biomolecules, including lipids, proteins, and DNA. Many techniques now exist that allow the measurement of the oxidative stress status of humans; the techniques are as diverse as blood tests for oxidized lipids, volatile hydrocarbons in breath, and oxidized DNA bases in urine. It is suggested that the more routine use of oxidative stress status measurements could be of significant use in clinical medicine.

摘要

我们生活的氧气环境会对包括脂质、蛋白质和DNA在内的所有生物分子持续产生一连串的氧化损伤。现在有许多技术可用于测量人类的氧化应激状态;这些技术多种多样,如检测血液中氧化脂质、呼出气体中的挥发性碳氢化合物以及尿液中氧化的DNA碱基。有人认为,更常规地使用氧化应激状态测量在临床医学中可能会有很大用处。

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