异丙肌苷增强干扰素的抗肿瘤作用。
Isoprinosine increases the antitumor action of interferon.
作者信息
Cerutti I, Chany C, Schlumberger J F
出版信息
Cancer Treat Rep. 1978 Nov;62(11):1971-4.
PMID:83190
Abstract
The association of relatively low doses of interferon with an immunostimulant (isoprinosine) enhances the antitumor effect of interferon. After combined treatment, the mean survival time, tumor incidence, and final survival rate are significantly increased in mice inoculated with 10(6) Crocker tumor 180/TG cells when compared to mice treated with interferon alone.
摘要
相对低剂量的干扰素与一种免疫刺激剂（异丙肌苷）联合使用可增强干扰素的抗肿瘤效果。联合治疗后，与单独使用干扰素治疗的小鼠相比，接种10(6)个克罗克肿瘤180/TG细胞的小鼠的平均存活时间、肿瘤发生率和最终存活率均显著提高。
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