Di Rocco C, Caldarelli M, Guzzetta F, Torrioli G
Institute of Neurosurgery, Catholic University Medical School, Rome, Italy.
Childs Nerv Syst. 1993 Apr;9(2):72-80. doi: 10.1007/BF00305311.
Nine children with perinatal occlusion of the middle cerebral artery, resulting in unilateral enlargement of one lateral cerebral ventricle associated with cortical atrophy and subcortical cavity formation, were operated on because of intractable epilepsy. All subjects exhibited mild to severe hemiparesis, localized in the right side of the body in six instances and in the left side in the three cases. All but one patient presented with some degree of psychomotor retardation. The surgical treatment consisted of the removal of the atrophic cerebral cortex. One child died after surgery because of disseminated intravascular coagulation. All the remaining eight children benefited from the operation, with a decrease in the hypertonia of the affected limbs and an improvement in dexterity and gait as well as in intellectual performance. Five patients could be considered seizure-free following the surgical treatment, and the remaining three experienced a significant reduction in the frequency of the seizures.
9名患有大脑中动脉围产期闭塞的儿童,导致一侧侧脑室单侧扩大,并伴有皮质萎缩和皮质下腔形成,因顽固性癫痫接受了手术。所有受试者均表现出轻度至重度偏瘫,6例位于身体右侧,3例位于左侧。除1名患者外,所有患者均有一定程度的精神运动发育迟缓。手术治疗包括切除萎缩的大脑皮质。1名儿童术后因弥散性血管内凝血死亡。其余8名儿童均从手术中获益,患侧肢体张力亢进减轻,灵活性、步态及智力表现均有改善。5例患者术后可视为无癫痫发作,其余3例癫痫发作频率显著降低。