Tanaka H, Tamura M, Kikuchi K, Kuwata F, Hirano Y, Hayashi K
Department of Bacteriology, Nihon University School of Dentistry, Tokyo, Japan.
Caries Res. 1993;27(2):130-4. doi: 10.1159/000261530.
Specific activities of lactate dehydrogenase (LDH) and its fructose 1,6-bisphosphate (FBP) dependency in the small amount of plaque formed on deciduous teeth were determined and compared between those from carious lesions and from sound surfaces. Although the caries-associated plaque showed a higher production of lactic acid than the plaque formed on sound surfaces, it occurred only when sufficient FBP was present. The proportion of activity of FBP-dependent LDH relative to that of total LDH varied much more in the caries-associated plaque than in the plaque formed on sound surfaces. Hence, the varying activity of FBP-dependent LDH might be a distinguishing feature of caries-associated plaque compared with plaque formed on sound surfaces.
测定了乳牙上形成的少量菌斑中乳酸脱氢酶（LDH）的比活性及其对1,6-二磷酸果糖（FBP）的依赖性，并比较了龋损部位菌斑与健康表面菌斑之间的差异。虽然与龋齿相关的菌斑比健康表面形成的菌斑产生更多的乳酸，但这仅在有足够FBP存在时才会发生。与健康表面形成的菌斑相比，与龋齿相关的菌斑中依赖FBP的LDH活性占总LDH活性的比例变化更大。因此，与健康表面形成的菌斑相比，依赖FBP的LDH活性变化可能是与龋齿相关菌斑的一个显著特征。
