手术后血液纤溶活性的变化（深静脉血栓形成和恶性疾病的影响）
Changes in the blood fibrinolytic activity after surgery (the effect of deep vein thrombosis and malignant disease.
作者信息
Browse N L, Gray L, Morland M
出版信息
Br J Surg. 1977 Jan;64(1):23-7. doi: 10.1002/bjs.1800640106.
The changes in blood fibrinolytic activity before and after operation have been investigated in 56 patients. The results have been analysed to assess the effect of the presence of malignant disease and the development of deep vein thombosis. The results show that patients with malignant disease and those with thrombosis have a fibrinolytic shut-down. This shut-down appears to be secondary to these two conditions and not the cause of the thrombosis. Patients without carcinoma and without thrombosis do not have a significant shut-down. The fibrinolytic shut-down results from a reduced release of activator from the peripheral store, not a reduction in the size of the store itself.
对56例患者手术前后的血液纤溶活性变化进行了研究。对结果进行了分析，以评估恶性疾病的存在和深静脉血栓形成的发展所产生的影响。结果表明，患有恶性疾病的患者和患有血栓形成的患者存在纤溶关闭现象。这种关闭似乎是这两种情况的继发结果，而非血栓形成的原因。没有癌症且没有血栓形成的患者没有明显的关闭现象。纤溶关闭是由于外周储存库中激活剂释放减少所致，而非储存库本身大小的减小。
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