Doutsu Y, Taniguchi H, Ashitani J, Ihi T, Sakamoto A, Matsukura S, Matsumoto S
Third Department of Internal Medicine, Medical College of Miyazaki.
Kansenshogaku Zasshi. 1993 May;67(5):491-5. doi: 10.11150/kansenshogakuzasshi1970.67.491.
A 41-year-old male visited our clinic complaining of cough and dirty hemosputum. Roentgenogram and CT scan of the chest revealed a cavitary nodule in the S1+2 of the left lung. After administration of antibiotics (CFIX, ASPC, FMOX, CLDM), the cavities were disappeared but the size of the nodule remained unchanged. Because the possibility of lung cancer could not be excluded, we underwent transbronchial brushing and bronchial lavage. Then, parasitic ova of Paragonimus westermani was detected in BALF, and an Ouchterlony's double diffusion test showed strong reaction against Paragonimus westermani antigen. The patient was successfully treated with praziquantel. Efficacy of the treatment was confirmed by a remarkable decrease of antibody titer measured by microplate-EIA.
一名41岁男性因咳嗽和咳出脏血痰前来我院就诊。胸部X光片和CT扫描显示左肺S1+2区有一个空洞性结节。使用抗生素（头孢克肟、阿洛西林、氟莫西尼、氯地霉素）治疗后，空洞消失，但结节大小未变。由于不能排除肺癌的可能性，我们进行了经支气管刷检和支气管灌洗。随后，在支气管肺泡灌洗（BALF）中检测到卫氏并殖吸虫的寄生虫卵，双向琼脂扩散试验显示对卫氏并殖吸虫抗原有强反应。该患者用吡喹酮成功治疗。通过酶联免疫吸附测定法（ELISA）检测抗体滴度显著下降，证实了治疗效果。
