Fundal uterine leiomyoma obscuring first-trimester transabdominal sonographic diagnosis of fetal holoprosencephaly. A case report.

With new techniques in transvaginal ultrasound, higher resolution allows the earlier diagnosis of fetal developmental anomalies. We describe a case of first-trimester antenatal diagnosis of alobar holoprosencephaly using transvaginal and perineal ultrasound that was obscured from transabdominal sonography by a large uterine leiomyoma.