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[青紫型心脏病患儿的正常血红蛋白水平。是缺铁性贫血吗?]

[Normal hemoglobin levels in children with cyanotic heart disease. Is it iron deficiency anemia?].

作者信息

Hågå P

机构信息

Barneavdelingen, Ullevål sykehus, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1993 May 30;113(14):1710-1.

PMID:8322297
Abstract

Decreased arterial oxygen saturation in cyanotic congenital heart disease causes a compensatory rise in haemoglobin and haematocrit levels. There is an inverse correlation between arterial oxygen saturation and haemoglobin/haematocrit. This holds true as long as the erythropoiesis is not restricted by other factors. The haematological values and arterial oxygen saturations of three children with cyanotic congenital heart disease are presented. They illustrate how iron deficiency causes discrepant values for arterial oxygen saturation and haemoglobin/haematocrit and that "normal" haemoglobin/haematocrit levels in such children may constitute anaemia. Measurements of MCV, MCH and serum ferritin reveal the existence of iron deficiency anaemia. Low grade iron medication is recommended for children with cyanotic congenital heart disease.

摘要

青紫型先天性心脏病患者动脉血氧饱和度降低会导致血红蛋白和血细胞比容水平代偿性升高。动脉血氧饱和度与血红蛋白/血细胞比容呈负相关。只要红细胞生成不受其他因素限制,这种关系就成立。本文呈现了三名青紫型先天性心脏病患儿的血液学指标和动脉血氧饱和度。这些指标表明缺铁如何导致动脉血氧饱和度与血红蛋白/血细胞比容值出现差异,以及此类患儿的“正常”血红蛋白/血细胞比容水平可能意味着贫血。平均红细胞体积、平均红细胞血红蛋白含量和血清铁蛋白的测量结果揭示了缺铁性贫血的存在。建议对青紫型先天性心脏病患儿进行低剂量铁剂治疗。

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