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直肠腺癌腹会阴联合切除术后的发病率和死亡率。

Morbidity and mortality following abdominoperineal resection for rectal adenocarcinoma.

作者信息

Petrelli N J, Nagel S, Rodriguez-Bigas M, Piedmonte M, Herrera L

机构信息

Roswell Park Cancer Institute, Department of Surgical Oncology and Endoscopy, Buffalo, New York 14263.

出版信息

Am Surg. 1993 Jul;59(7):400-4.

PMID:8323072
Abstract

From 1979 through 1986, 56 patients, 38 males (68%) and 18 females (32%), underwent an abdominoperineal resection with a wide perineal dissection for primary adenocarcinoma of the rectum. The open perineal wounds required a mean time of 6 months to completely heal. Estimated blood loss by the surgeon ranged from 200 ml to 4200 ml with a mean of 1112 ml and a median of 1000 ml. Twenty-six patients (46%) developed postoperative or intraoperative complications. Nineteen patients (34%) underwent incidental surgery with no associated morbidity. The most commonly occurring complication was impotence in 69% of male patients. The next most common complication was bladder dysfunction with urinary retention in 14 patients (25%) and urinary incontinence in five patients (9%). There were two postoperative deaths (4%). Although the morbidity was significant, greater than 90% of the complications were treatable and resolved without major sequellae.

摘要

1979年至1986年期间,56例患者接受了腹会阴联合切除术及广泛的会阴清扫术,以治疗原发性直肠癌,其中男性38例(68%),女性18例(32%)。开放性会阴伤口平均需要6个月才能完全愈合。外科医生估计的失血量在200毫升至4200毫升之间,平均为1112毫升,中位数为1000毫升。26例患者(46%)出现术后或术中并发症。19例患者(34%)接受了意外手术,未出现相关发病率。最常见的并发症是69%的男性患者出现阳痿。第二常见的并发症是膀胱功能障碍,14例患者(25%)出现尿潴留,5例患者(9%)出现尿失禁。有2例术后死亡(4%)。尽管发病率较高,但超过90%的并发症是可治疗的,且未留下严重后遗症而得以解决。

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