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[二尖瓣机械瓣膜置换术后心房黏液瘤复发——附1例报告]

[The recurrence of an atrial myxoma in a patient with a mechanical mitral prosthesis--apropos a case].

作者信息

Nunes H, Ramos J M, Abreu J, Cotrim C, Pereira H, Figueiredo L, da Cruz G, Salomão S

机构信息

Serviço de Cardiologia, Hospital de Santa Marta, Lisboa.

出版信息

Rev Port Cardiol. 1993 May;12(5):461-8, 407.

PMID:8323783
Abstract

Recurrence of cardiac myxoma after surgery is an uncommon situation, particularly if a wide excision of the tissue under the tumour has been done. The authors report a case of a 54-year-old male presenting with a left atrial myxoma near the mitral valve, which had to be replaced by a mechanical prosthetic valve during the removal of the tumour. One year later, he was admitted to hospital with persistent fever, weight loss, and congestive heart failure. After a positive hemoculture, intravenous antibiotherapy was initiated, and twice modified because of relapsing fever. Six weeks later, he was transferred to our institution, after an episode of severe acute pulmonary edema. 2D-Doppler echocardiography suggested the possibility of prosthesis dysfunction, revealing a transprothetic diastolic flow with a high peak velocity and moderately elevated pressure half-time. No intra-atrial masses were visualized. Computed tomography was also inconclusive, because of multiple artifacts produced by the prosthesis. These results led to the performance of a cardiac catheterization with contrast ventriculography, which revealed the presence of a transprothetic gradient, and mild mitral regurgitation. The patient was submitted to cardiac surgery, which revealed a recurrent pedunculated left atrial myxoma, with mechanical obstruction of the mitral prosthetic valve. No signs of endocarditis were found. Recurrent cardiac myxomas are reviewed and discussed, as well as the specific problems of the present case, namely the presence of a mechanical prosthetic mitral valve and the initial hemoculture results, with consequent diagnostic delay.

摘要

心脏黏液瘤术后复发是一种罕见情况,尤其是在对肿瘤下方组织进行广泛切除的情况下。作者报告了一例54岁男性患者,其左心房黏液瘤靠近二尖瓣,在切除肿瘤过程中不得不置换机械人工瓣膜。一年后,他因持续发热、体重减轻和充血性心力衰竭入院。血培养呈阳性后,开始静脉抗生素治疗,并因反复发热两次调整治疗方案。六周后,在发生严重急性肺水肿后,他被转至我们机构。二维多普勒超声心动图提示人工瓣膜功能障碍的可能性,显示人工瓣膜舒张期血流峰值速度高且压力减半时间中度升高。未发现心房内肿块。计算机断层扫描也无定论,因为人工瓣膜产生了多个伪影。这些结果导致进行了心脏导管造影及对比心室造影,结果显示存在人工瓣膜压差及轻度二尖瓣反流。患者接受了心脏手术,术中发现一个带蒂的左心房黏液瘤复发,机械性阻塞二尖瓣人工瓣膜。未发现心内膜炎迹象。本文对复发性心脏黏液瘤进行了回顾和讨论,以及本病例的具体问题,即存在机械二尖瓣人工瓣膜和最初的血培养结果,导致诊断延迟。

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