Pomponi M, Marta M
Biochemistry Department, Catholic University, School of Medicine, Roma, Italy.
Aging (Milano). 1993 Apr;5(2):135-9. doi: 10.1007/BF03324140.
Gaetano Perusini merits a great deal more credit for his work on the elaboration of the concepts regarding what is now called Alzheimer's disease (AD). Perusini's work in Alzheimer's laboratory and his subsequent studies have been, if not neglected, largely unmentioned. This article is an attempt to report a fascinating piece of medical history in order to redress the balance. Surely, Perusini's work deserves to be reexamined. The same applies to Fischer's investigation. Some of the puzzles discussed by Perusini are still unresolved.
加埃塔诺·佩鲁西尼在阐述如今被称为阿尔茨海默病(AD)的概念方面所做的工作,理应得到更多赞誉。佩鲁西尼在阿尔茨海默实验室的工作以及他随后的研究,即便没有被忽视,也在很大程度上未被提及。本文试图讲述一段引人入胜的医学史,以恢复平衡。当然,佩鲁西尼的工作值得重新审视。菲舍尔的研究也是如此。佩鲁西尼所讨论的一些谜题至今仍未得到解决。