Lee D, Goldstein E J, Citron D M, Ross S
Department of Family Practice, Santa Monica Hospital Medical Center, California.
Clin Infect Dis. 1993 Jun;16 Suppl 4:S263-5. doi: 10.1093/clinids/16.supplement_4.s263.
We describe a patient with empyema due to Bacteroides gracilis and a viridans streptococcus. Therapy with both cefoxitin and imipenem failed, and the patient remained symptomatic even after thoracotomy was performed. Clinical response occurred after initiation of clindamycin therapy. The susceptibilities of the patient's isolate, other clinical strains, and the reference strain were determined by an agar dilution method. The isolates were generally susceptible to all the agents tested; however, some strains were resistant to clindamycin (MIC, 8 micrograms/mL), penicillin G (MIC90, 16 micrograms/mL), and metronidazole (MIC90, 64 micrograms/mL). The B. gracilis isolate from our patient was susceptible to all agents tested, including cefoxitin and imipenem.
我们描述了一名因纤细拟杆菌和草绿色链球菌引起脓胸的患者。使用头孢西丁和亚胺培南治疗均失败，即使在进行开胸手术后患者仍有症状。克林霉素治疗开始后出现了临床反应。通过琼脂稀释法测定了患者分离株、其他临床菌株和参考菌株的药敏情况。分离株通常对所有测试药物敏感；然而，一些菌株对克林霉素（MIC，8微克/毫升）、青霉素G（MIC90，16微克/毫升）和甲硝唑（MIC90，64微克/毫升）耐药。我们患者的纤细拟杆菌分离株对所有测试药物敏感，包括头孢西丁和亚胺培南。
