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[The efficacy of phenol antioxidants in vitro and in vivo].

作者信息

Vadziuk S N, Gorodetskiĭ I T, Faĭfura V V, Klishch I N

出版信息

Eksp Klin Farmakol. 1993 Jan-Feb;56(1):47-8.

PMID:8324475
Abstract

The antioxidative activity of ionol, 2,2'methylene-bis(6-tert-butyl-4-methylphenol), 2,2-ethylenebis (6-tert-butyl-4-methylphenol), 2,2-propylenebis (6-tert-butyl-4-methylphenol, 2,2-butylenebis (6-tert-butyl-4-methylphenol) was studied in models and in albino rats with experimental hyperthyroidism. The most intensive extinguishing of induced chemiluminescence was found to be produced by 2,2-methylenebis (6-tert-butyl-4-methylphenol) and 2,2-ethylenebis (6-tert-butyl-4-methylphenol). These substances produced the most inhibitory effects on lipid peroxidation in the heart of hyperthyroidism animals.

摘要

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