Satou K, Furuichi E, Takiguchi K, Takagi T, Kuhara S
Educational Center for Information Processing, Kyushu University, Fukuoka, Japan.
Comput Appl Biosci. 1993 Jun;9(3):259-65. doi: 10.1093/bioinformatics/9.3.259.
We have developed a deductive database system PACADE for analyzing 3-D and secondary structures of protein. The PACADE system consists of a relational database created from Protein Data Bank and a deductive engine DEE based on logic programming. It has the following features: (1) The system has an inference mechanism. This means by which users can easily write and check biological hypotheses using logical and declarative rules instead of procedural programs. (2) The relational database of the PACADE system stores data on both 3-D and secondary structures of protein. The integration of this two level structure makes feasible an abstract representation of the protein structure. We describe herein the design, functions, and implementation of this PACADE system.
我们开发了一个用于分析蛋白质三维结构和二级结构的演绎数据库系统PACADE。PACADE系统由一个基于蛋白质数据库创建的关系数据库和一个基于逻辑编程的演绎引擎DEE组成。它具有以下特点：（1）该系统具有推理机制。这意味着用户可以通过逻辑和声明性规则而非过程性程序轻松编写和检验生物学假设。（2）PACADE系统的关系数据库存储有关蛋白质三维结构和二级结构的数据。这种两级结构的整合使得蛋白质结构的抽象表示成为可能。本文我们将描述这个PACADE系统的设计、功能和实现。
