Hames C G, Rose K, Knowles M, Davis C E, Tyroler H A
Evans County Heart Research, Claxton, Ga.
Cardiology. 1993;82(2-3):122-36. doi: 10.1159/000175863.
The Evans County Heart Study was initiated to compare the epidemiology of coronary heart disease (CHD) of black and white residents of a southeastern United States community. The study was prompted by a clinical observation that CHD appeared to be less frequent in black than white patients, despite a much higher prevalence and greater severity of hypertension in blacks. A total community-based, closed cohort study was initiated with a prevalence survey in 1960-1962. The 20-year follow-up experience of the Evans County cohort confirmed the importance of the major risk factors of serum cholesterol, smoking and blood pressure for middle age and older, black and white men and women for CHD, cardiovascular disease (CVD) and all-cause mortality. Black men were less likely to die of CHD than white men, and this relative protectiveness increased upon adjusting for risk factors and also increased with age. The relative protectiveness of black men for CHD mortality was also reflected in lower black than white CVD and all-cause mortality in men 65 years of age and older.
埃文斯县心脏研究旨在比较美国东南部一个社区黑人和白人居民冠心病(CHD)的流行病学情况。该研究是由一项临床观察引发的,即尽管黑人高血压的患病率更高、病情更严重,但冠心病在黑人患者中似乎比白人患者更为少见。1960年至1962年开展了一项基于社区的总体封闭队列研究及患病率调查。埃文斯县队列20年的随访经验证实了血清胆固醇、吸烟和血压等主要危险因素对于中老年黑人和白人男性及女性患冠心病、心血管疾病(CVD)和全因死亡率的重要性。黑人男性死于冠心病的可能性低于白人男性,在对危险因素进行调整后,这种相对的保护作用增强,并且随着年龄增长而增加。65岁及以上男性中,黑人男性对冠心病死亡率的相对保护作用也体现在黑人的心血管疾病和全因死亡率低于白人。