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医生对慢性阻塞性肺疾病(COPD)的认知与管理。

Physician perceptions and management of COPD.

作者信息

Kesten S, Chapman K R

机构信息

Asthma Centre, Toronto Hospital, Ontario, Canada.

出版信息

Chest. 1993 Jul;104(1):254-8. doi: 10.1378/chest.104.1.254.

DOI:10.1378/chest.104.1.254
PMID:8325079
Abstract

To assess awareness and understanding of obstructive airway diseases by primary-care physicians, the authors surveyed a randomly selected population of 75 primary care practitioners. During one-on-one interviews, physicians were presented with a standardized case scenario and a subsequent series of open-ended questions concerning asthma and COPD. Each respondent was presented in randomized fashion with one of two versions of a case description of a hypothetical 52-year-old male smoker with a recent upper respiratory tract infection and persistent productive cough. The only difference between case descriptions was that one included explicit reference to an earlier tentative diagnosis of chronic bronchitis (CB version); the other description made no specific mention of this diagnostic term (NCB version). Chest radiographs were requested by 80 percent of physicians and sputum cultures by 50 percent, these percentages not differing significantly between CB and NCB groups. Spirometry was requested less often than either of the foregoing tests (21 percent). The CB group requested spirometry significantly more often than the NCB group (38 percent vs 5 percent, p < 0.05). The most frequently mentioned primary diagnosis was bronchitis/pneumonia (33 percent), followed by bronchitis (28 percent) and chronic bronchitis (16 percent), all of which were similar in both groups. However, the diagnostic term "COPD" was the primary diagnosis in 16 percent of the CB group, compared with 8 percent in the NCB group (p > 0.05). Oral antibiotics were the most frequently chosen first-line drug therapy (63 percent). In subsequent questions concerning the management of obstructive airway diseases, primary practitioners distinguished COPD from asthma conceptually, but their prescribed therapy for the two disorders was less distinct. beta 2-agonists were selected most frequently and similarly as initial therapy for both disorders (53 percent). Minor differences between first-line therapeutic choices included nonsignificant trends toward the more frequent mention of anticholinergic bronchodilators for COPD than for asthma (10 percent vs 0 percent) and the more frequent selection of inhaled corticosteroids for asthma (12 percent vs 5 percent). The authors conclude that to the extent that questionnaire responses reflect actual practice, primary care practitioners (1) have a low index of suspicion for obstructive airway disease, (2) markedly underutilized spirometry as a screening tool, (3) consider beta 2-agonists first-line therapy for COPD and asthma, and (4) despite considering COPD and asthma different disease processes, choose similar medications for each disorder.

摘要

为评估基层医疗医生对阻塞性气道疾病的认知和理解,作者对75名随机挑选的基层医疗从业者进行了调查。在一对一访谈中,向医生展示了一个标准化的病例场景以及随后一系列关于哮喘和慢性阻塞性肺疾病(COPD)的开放式问题。每位受访者以随机方式收到两个版本之一的病例描述,该病例描述的是一名52岁的男性吸烟者,近期患有上呼吸道感染且持续咳痰。病例描述之间的唯一区别在于,一个明确提及了早期慢性支气管炎的初步诊断(CB版本);另一个描述未具体提及该诊断术语(NCB版本)。80%的医生要求进行胸部X光检查,50%的医生要求进行痰培养,CB组和NCB组的这些百分比差异不显著。要求进行肺功能测定的频率低于上述任何一项检查(21%)。CB组要求进行肺功能测定的频率显著高于NCB组(38%对5%,p<0.05)。最常提及的初步诊断是支气管炎/肺炎(33%),其次是支气管炎(28%)和慢性支气管炎(16%),两组情况相似。然而,诊断术语“COPD”在CB组中作为初步诊断的比例为16%,而在NCB组中为8%(p>0.05)。口服抗生素是最常选择的一线药物治疗(63%)。在随后关于阻塞性气道疾病管理的问题中,基层医疗从业者在概念上能够区分COPD和哮喘,但他们针对这两种疾病所开的治疗药物差异较小。β2受体激动剂作为这两种疾病的初始治疗药物被最频繁且相似地选用(53%)。一线治疗选择的细微差异包括,与哮喘相比,COPD更常提及使用抗胆碱能支气管扩张剂(10%对0%)以及哮喘更常选用吸入性糖皮质激素(12%对5%),但这些差异均无统计学意义。作者得出结论,就问卷回复反映实际临床实践的程度而言,基层医疗从业者(1)对阻塞性气道疾病的怀疑指数较低;(2)显著未充分利用肺功能测定作为筛查工具;(3)将β2受体激动剂视为COPD和哮喘的一线治疗药物;(4)尽管认为COPD和哮喘是不同的疾病过程,但为每种疾病选择的药物相似。

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