Allan B D, van Saarloos P P, Russo A V, Cooper R L, Constable I J
Lions Eye Institute, Nedlands, Western Australia.
Eye (Lond). 1993;7 ( Pt 1):47-52. doi: 10.1038/eye.1993.11.
The argon fluoride (ArF) excimer laser at 193 nm ablates the ocular tissues with a new order of precision and virtually no adjacent damage. A glaucoma filtration operation has been designed in which small-bore sclerostomies are created using the ArF excimer laser delivered through an open mask. The mask plicates the conjunctiva at the limbus prior to ablation. Removing the mask at the end of the procedure allows the conjunctiva to relax back to its original position, separating the conjunctival and scleral wounds. Formal conjunctival dissection is thus avoided. Feasibility studies in cadaver pig eyes, using a fluence per pulse of 400 mJ/cm2 and a pulse repetition rate of 20 Hz, indicate that sclerostomies of 300 microns diameter can be reliably formed if an en-face air jet is built into the mask to raise the pressure in the target area, preventing aqueous flooding.
波长为193纳米的氟化氩（ArF）准分子激光以一种全新的精准度对眼部组织进行消融，几乎不会造成相邻组织损伤。现已设计出一种青光眼滤过手术，该手术使用通过开放式面罩发射的ArF准分子激光来制作小口径巩膜造瘘口。在消融前，面罩会在角膜缘处折叠结膜。手术结束时移除面罩可使结膜松弛回到其原始位置，从而分离结膜伤口和巩膜伤口。这样就避免了进行正式的结膜剥离。在猪尸体眼上进行的可行性研究表明，若在面罩中内置一个正面喷气装置以提高目标区域的压力，防止房水外溢，当每脉冲能量密度为400 mJ/cm²且脉冲重复频率为20 Hz时，能够可靠地形成直径为300微米的巩膜造瘘口。
