Nevid N J, Meier A H
Department of Zoology and Physiology, Louisiana State University, Baton Route 70803.
Dev Comp Immunol. 1993 May-Jun;17(3):221-8. doi: 10.1016/0145-305x(93)90041-n.
The circadian variation of scale allograft rejection was studied in teleost fish maintained on 12-h daily photoperiods (LD 12:12). Immune activity, measured by melanophore breakdown, was two to three times greater during the dark than during the light whether scale allografts were transplanted at light onset or light offset. Because rejection occurred predominantly at night, survival times of both primary and secondary allografts were about 0.4 days longer when the transplants were made at light onset. Immune activity undergoes a robust daily variation in a teleost fish.
在保持12小时日常光周期（LD 12:12）的硬骨鱼中研究了鳞片同种异体移植的昼夜变化。通过黑素细胞分解测量的免疫活性，无论鳞片同种异体移植是在光照开始时还是光照结束时进行移植，在黑暗期间比在光照期间大两到三倍。由于排斥反应主要发生在夜间，当在光照开始时进行移植时，初次和二次同种异体移植的存活时间都长约0.4天。硬骨鱼的免疫活性每天都有显著变化。
