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[肺门淋巴结孤立性淀粉样变性]

[Isolated amyloidosis of hilar lymph nodes].

作者信息

Plöckinger B, Müller M R, Eckersberger F

机构信息

2. Universitäts-Frauenklinik, Wien, Osterreich.

出版信息

Langenbecks Arch Chir. 1993;378(3):167-70. doi: 10.1007/BF00184467.

Abstract

Pseudotumoral mediastinal and pulmonary amyloidosis occur infrequently and may be confused with other tumors that are found more commonly in this region. Enlargement of hilar lymph nodes in the absence of pulmonary involvement is extremely rare. We report a case of nodular amyloidosis of the hilar lymph nodes that was studied using different diagnostic and radiologic methods. A previously healthy 79-year-old man presented with a large right hilar mass detected on routine chest roentgenography. The extensive mass behaved like a solid tumor and mimicked a bronchogenic carcinoma. At thoracotomy, frozen sections revealed the tumor to consist of kappa-light-chain amyloid. In light of the irresectibility of the tumor, thoracotomy was ended as open biopsy. Immunoelectrophoretic analyses of the plasma and urine showed no evidence of a paraprotein immunoglobulin or light chains. The patient was discharged without symptoms of disease. Different diagnostic procedures before and after surgery are discussed.

摘要

假性肿瘤性纵隔和肺淀粉样变性很少见,可能会与该区域更常见的其他肿瘤相混淆。在无肺部受累情况下肺门淋巴结肿大极为罕见。我们报告一例肺门淋巴结结节性淀粉样变性病例,该病例采用了不同的诊断和放射学方法进行研究。一名既往健康的79岁男性在常规胸部X线检查时发现右肺门有一巨大肿块。该广泛肿块表现为实体瘤,类似支气管源性癌。开胸手术时,冰冻切片显示肿瘤由κ轻链淀粉样蛋白组成。鉴于肿瘤无法切除,开胸手术以开放活检告终。血浆和尿液的免疫电泳分析未发现副蛋白免疫球蛋白或轻链的证据。患者出院时无疾病症状。文中讨论了手术前后不同的诊断程序。

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