Rosen M
Elwyn, Inc., PA 19063.
Ment Retard. 1993 Jun;31(3):177-8.
Recent advances in recombinant DNA studies have been productive in identifying specific genetic loci for several disorders believed to be associated with mental retardation. In this paper the methodology of many such studies was criticized as failing to demonstrate an association between the behavior phenotype and the genetic marker. A more appropriate methodology using a multitrait-multimethod approach was suggested.
重组DNA研究的最新进展在识别几种被认为与智力迟钝相关的疾病的特定基因位点方面成果丰硕。在本文中，许多此类研究的方法受到批评，因为它们未能证明行为表型与基因标记之间存在关联。有人提出了一种使用多特质-多方法途径的更合适的方法。
