Tsuzuki N, Suzuki K, Matsuno A, Hasizume K
Department of Neurosurgery, National Defence Central Hospital.
No Shinkei Geka. 1993 Jul;21(7):641-4.
A case of growing skull fracture was reported with some considerations on the literature. At the age of 1 year, the patient fell down stairs and struck the right occipital region, but did not receive any treatment at that time. At the age of 19 years, he suffered from several epileptic attacks and was admitted to our ward. Plain craniograms showed a right occipital bone defect measuring 7 x 3 cm in size. CT scan demonstrated a cystic lesion just beneath a membranous substance existing at the bone defect. MRI revealed cystic encephalomalacia underlying the cyst very clearly. At the operation the bone defect was found to be replaced by the granulation tissue which was examined microscopically. Under the granulation tissue, a cyst filled with yellowish fluid and surrounding gliotic brain was found. The dural tear was noticed to be much wider than the bone defect. A dural plasty with LYODURA and a cranioplasty with methacrylic resin were performed. Microscopic examination revealed the granulation tissue to be a fibroglial cicatrix. According to these findings, we concluded that the contused and swollen brain tissue which had herniated through the dural tear had enlarged the skull fracture and formed a fibroglial cicatrix with subcutaneous tissue. It is emphasized that MRI combined with CT scan is an indispensable procedure for diagnosis of growing skull fracture, and microscopic examination contributes to an understanding of its pathogenesis.
报告了1例生长性颅骨骨折病例,并对相关文献进行了一些探讨。患者1岁时从楼梯上摔下,撞到右枕部,但当时未接受任何治疗。19岁时,他出现了几次癫痫发作,随后入住我们科室。头颅X线平片显示右侧枕骨有一大小为7×3 cm的骨缺损。CT扫描显示在骨缺损处的一层膜状物质下方有一个囊性病变。MRI非常清晰地显示囊肿下方存在囊性脑软化。手术时发现骨缺损被肉芽组织替代,并对其进行了显微镜检查。在肉芽组织下方,发现一个充满淡黄色液体的囊肿以及周围胶质增生的脑组织。发现硬脑膜撕裂比骨缺损宽得多。采用LYODURA进行硬脑膜修补术,并用甲基丙烯酸树脂进行颅骨成形术。显微镜检查显示肉芽组织为纤维胶质瘢痕。根据这些发现,我们得出结论,通过硬脑膜撕裂疝出的挫伤和肿胀的脑组织扩大了颅骨骨折,并与皮下组织形成了纤维胶质瘢痕。强调MRI结合CT扫描是诊断生长性颅骨骨折不可或缺的检查方法,而显微镜检查有助于了解其发病机制。