Godaux E, Cheron G
Laboratory of Neurophysiology, University of Mons-Hainaut, Belgium.
Neurosci Lett. 1993 Apr 30;153(2):149-52. doi: 10.1016/0304-3940(93)90309-9.
Recent theoretical studies have proposed that the vestibular commissure is a major component of the horizontal gaze-holding system. In order to test this hypothesis, we disrupted the vestibular commissure of the cat by a parasagittal cut running between an abducens nucleus and the adjacent medial vestibular nucleus. Successfully lesioned cats suffered of a characteristic syndrome. In the light, gaze holding was impaired when the animal was looking toward the side of the lesion, but normal when looking toward the opposite side. We conclude (1) that the vestibular commissure is a component of the gaze-holding system, (2) that the vestibular commissure is less essential for gaze holding than other structures as the nucleus prepositus hypoglossi, and (3) that the horizontal gaze-holding system consists of two halves, each being more active in ipsilateral than in contralateral gaze.
最近的理论研究表明，前庭连合是水平凝视稳定系统的主要组成部分。为了验证这一假设，我们通过在展神经核和相邻的内侧前庭核之间进行矢状旁切口来破坏猫的前庭连合。成功损伤的猫出现了一种特征性综合征。在光照下，当动物看向损伤侧时，凝视稳定受到损害，但看向对侧时则正常。我们得出以下结论：（1）前庭连合是凝视稳定系统的一个组成部分；（2）前庭连合对于凝视稳定的重要性低于其他结构，如舌下前置核；（3）水平凝视稳定系统由两个部分组成，每一部分在同侧凝视时比在对侧凝视时更活跃。
