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庚酸炔诺酮和醋酸甲羟孕酮对葡萄糖、胰岛素、生长激素及脂质的短期影响。

Short-term effects of norethisterone oenanthate and medroxyprogesterone acetate on glucose, insulin, growth hormone, and lipids.

作者信息

Dhall K, Kumar M, Rastogi G K, Devi P K

出版信息

Fertil Steril. 1977 Feb;28(2):156-8. doi: 10.1016/s0015-0282(16)42374-5.

DOI:10.1016/s0015-0282(16)42374-5
PMID:832727
Abstract

The effects on carbohydrate and lipid metabolism in 24 healthy female subjects of the long-acting steroid contraceptives norethisterone oenanthate (200 mg) (11 subjects) and depo-medroxyprogesterone acetate (150 mg) (13 subjects) were studied. The subjects were between the ages of 18 and 25 years, with a history of normal menstrual periods. Pretreatment levels of plasma cholesterol, plasma triglycerides, phospholipids, blood glucose, insulin, and growth hormone were compared with those obtained 3 weeks and 12 weeks after the initial injections. There were no statistically significant differences from the pretreatment levels in any of the values obtained at 3 weeks and 12 weeks in either group.

摘要

研究了长效甾体避孕药庚酸炔诺酮(200毫克)(11名受试者)和醋酸甲羟孕酮(150毫克)(13名受试者)对24名健康女性受试者碳水化合物和脂质代谢的影响。受试者年龄在18至25岁之间,月经周期正常。将血浆胆固醇、血浆甘油三酯、磷脂、血糖、胰岛素和生长激素的治疗前水平与初次注射后3周和12周时的水平进行比较。两组在3周和12周时获得的任何值与治疗前水平相比均无统计学显著差异。

相似文献

1
Short-term effects of norethisterone oenanthate and medroxyprogesterone acetate on glucose, insulin, growth hormone, and lipids.庚酸炔诺酮和醋酸甲羟孕酮对葡萄糖、胰岛素、生长激素及脂质的短期影响。
Fertil Steril. 1977 Feb;28(2):156-8. doi: 10.1016/s0015-0282(16)42374-5.
2
A prospective, one-year study on the effects of two long acting injectable contraceptives (depot-medroxyprogesterone acetate and norethisterone oenanthate) on serum and lipoprotein lipids.一项关于两种长效注射用避孕药(醋酸甲羟孕酮和庚酸炔诺酮)对血清和脂蛋白脂质影响的前瞻性一年研究。
Horm Metab Res. 1992 Feb;24(2):85-9. doi: 10.1055/s-2007-1003262.
3
Effect of injectable contraceptives Depo-Provera and norethisterone oenanthate on pituitary gonadotropin response to luteinizing hormone-releasing hormone.
Fertil Steril. 1978 Nov;30(5):545-8. doi: 10.1016/s0015-0282(16)43635-6.
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Medroxyprogesterone acetate and carbohydrate metabolism: measurement of glucose, insulin, and growth hormone during 6 months' time.醋酸甲羟孕酮与碳水化合物代谢:6个月期间葡萄糖、胰岛素和生长激素的测量
Fertil Steril. 1970 Jun;21(6):457-63.
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The effects of medroxyprogesterone acetate on carbohydrate metabolism: measurements of glucose, insulin, and growth hormone after twelve months' use.醋酸甲羟孕酮对碳水化合物代谢的影响:使用十二个月后的血糖、胰岛素及生长激素测定
Fertil Steril. 1972 Apr;23(4):239-44.
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Multinational comparative clinical evaluation of two long-acting injectable contraceptive steroids: norethisterone oenanthate and medroxyprogesterone acetate. 1. Use-effectiveness.两种长效注射用避孕甾体激素的多国比较临床评估:庚酸炔诺酮和醋酸甲羟孕酮。1. 使用效果。
Contraception. 1977 May;15(5):513-33. doi: 10.1016/0010-7824(77)90102-0.
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Effects of medroxyprogesterone acetate on serum insulin and growth hormone levels in diabetics and potential diabetics.醋酸甲羟孕酮对糖尿病患者及潜在糖尿病患者血清胰岛素和生长激素水平的影响。
Obstet Gynecol. 1969 Mar;33(3):383-9.
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Long-term use of an injectable contraceptive: effect of depot-norethisterone oenanthate on carbohydrate metabolism.长效注射用避孕药:庚酸炔诺酮对碳水化合物代谢的影响。
Contraception. 1988 Jan;37(1):53-60. doi: 10.1016/0010-7824(88)90148-5.
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The effects of depo-provera on carbohydrate, lipids and vitamin metabolism.醋酸甲羟孕酮对碳水化合物、脂质和维生素代谢的影响。
J Steroid Biochem. 1979 Jul;11(1B):475-81. doi: 10.1016/0022-4731(79)90070-0.
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A comparison of the long-acting contraceptive agents norethisterone oenanthate and medroxyprogesterone acetate.长效避孕药庚炔诺酮与醋酸甲羟孕酮的比较。
Aust N Z J Obstet Gynaecol. 1971 Nov;11(4):233-6. doi: 10.1111/j.1479-828x.1971.tb00484.x.

引用本文的文献

1
Effect of injectable and oral contraceptives on glucose and insulin levels.注射用和口服避孕药对血糖和胰岛素水平的影响。
Obstet Gynecol. 2011 Jan;117(1):41-47. doi: 10.1097/AOG.0b013e318202ac23.
2
The influence of high doses of oral medroxyprogesterone acetate on glucose tolerance, serum insulin levels and adrenal response to ACTH. A study of 17 patients under treatment for endometrial cancer.大剂量口服醋酸甲羟孕酮对葡萄糖耐量、血清胰岛素水平及肾上腺对促肾上腺皮质激素反应的影响。对17例子宫内膜癌治疗患者的研究。
Arch Gynecol. 1980;230(1):9-13. doi: 10.1007/BF02108593.
3
Long acting contraceptives. Present status.
长效避孕药。现状。
Drugs. 1983 Jun;25(6):570-609. doi: 10.2165/00003495-198325060-00003.
4
Metabolic side-effects of injectable depot-medroxyprogesterone acetate, 150 mg three-monthly, in undernourished lactating women. WHO Task Force on Long-acting Agents for Fertility Regulation.150毫克醋酸甲羟孕酮长效注射剂每三个月一次用于营养不良哺乳期妇女的代谢副作用。世界卫生组织生育调节长效制剂特别工作组
Bull World Health Organ. 1986;64(4):587-94.