Reske S N, Karstens J H, Henrich M M, Sohn M, Glöckner W, Jakse G, Büll U
Klinik für Nuklearmedizin der RWTH, Klinikum Aachen, FRG.
Nuklearmedizin. 1993 Jun;32(3):111-9.
The results of immunoscintigraphy of haematopoetic bone marrow were compared with those of conventional bone scanning in 141 patients with malignant diseases. Marrow scans showed more metastatic lesions than bone scanning in all patient subgroups, resulting in a significantly more extended skeletal involvement. CT was concordant in 83.3% of 323 skeletal regions with bone marrow scanning. Bone marrow scans of 30 control patients with benign disease were abnormal only in 7 of 2135 skeletal regions in 3 patients. In malignant lymphoma, bone marrow histology or aspiration cytology was concordantly positive in 14 or negative in 17 patients. Immunoscintigraphy of haematopoetic bone marrow provides a reliable, sensitive and safe novel approach towards the non-invasive evaluation of metastatic spread to the skeleton.
对141例恶性疾病患者的造血骨髓免疫闪烁扫描结果与传统骨扫描结果进行了比较。在所有患者亚组中，骨髓扫描显示的转移灶比骨扫描更多，导致骨骼受累范围明显更广。在323个骨骼区域中，CT与骨髓扫描的一致性为83.3%。30例良性疾病对照患者的骨髓扫描仅在3例患者的2135个骨骼区域中的7个区域异常。在恶性淋巴瘤中，14例患者的骨髓组织学或穿刺细胞学检查结果一致为阳性，17例患者为阴性。造血骨髓免疫闪烁扫描为骨骼转移扩散的无创评估提供了一种可靠、灵敏且安全的新方法。
