吉氏巴贝斯虫在幼龄红细胞中优先增殖的直接证据。
Direct evidence for preferential multiplication of Babesia gibsoni in young erythrocytes.
作者信息
Murase T, Iwai M, Maede Y
机构信息
Department of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
出版信息
Parasitol Res. 1993;79(4):269-71. doi: 10.1007/BF00932180.
To clarify the effect of the age of host erythrocytes on the multiplication of Babesia parasites, B. gibsoni was cultured together with reticulocytes, immature erythrocytes, or mature erythrocytes from dogs. Parasitemia reached peak levels (34.1% +/- 15.8%) at cultivation day 8 in immature-erythrocyte culture, whereas the highest parasitemia attained in mature-cell culture was only 3.6% +/- 2.2% at day 5. These results clearly demonstrate that B. gibsoni parasites preferentially invade and multiply in young erythrocytes rather than in mature cells.
为阐明宿主角红细胞的年龄对巴贝斯虫寄生虫增殖的影响，将吉氏巴贝斯虫与犬的网织红细胞、未成熟红细胞或成熟红细胞共同培养。在未成熟红细胞培养中，虫血症在培养第8天达到峰值水平（34.1%±15.8%），而在成熟细胞培养中，第5天达到的最高虫血症仅为3.6%±2.2%。这些结果清楚地表明，吉氏巴贝斯虫寄生虫优先侵入年轻红细胞并在其中增殖，而非在成熟细胞中。
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