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[I型人类嗜T淋巴细胞病毒(HTLV-I)携带者的葡萄膜炎——2. 临床特征分析]

[Uveitis in human T-lymphotropic virus type I (HTLV-I) carriers--2. An analysis of clinical features].

作者信息

Yoshimura K, Shimada N, Shirao M, Mochizuki M, Araki S, Miyata N, Yamaguchi K, Takatsuki K, Watanabe T, Mori S

机构信息

Department of Ophthalmology, Kurume University School of Medicine, Japan.

出版信息

Nippon Ganka Gakkai Zasshi. 1993 Jun;97(6):733-40.

PMID:8328342
Abstract

The clinical features of human T-lymphotropic virus type (HTLV-I) uveitis, an idiopathic uveitis in HTLV-I seropositive patients, were analyzed in a hospital located in an area where HTLV-I was endemic (Miyakonojo, Miyazaki). A total of 61 patients (25 males and 31 females) with HTLV-I uveitis were the subjects of the analysis. Intermediate uveitis with moderate to severe vitreous opacities accompanied by mild iritis and retinal vasculitis was the most characteristic feature, and was observed in the majority of the patients (66% of all or 84% in young adult patients between 20 and 49 years of age). The uveitis affected one eye in 57% and both eyes in 43% of the patients, with subacute onset of floaters and foggy vision. The uveitis responded well to therapy with topical or systemic corticosteroids, but recurred in many cases. A significant number of patients (15% of all and 25% of female patients) had a previous history of Graves' disease with hyperthyroidism.

摘要

在宫崎县都城市(HTLV-I 地方性流行地区)的一家医院,对人类嗜 T 淋巴细胞病毒 1 型(HTLV-I)葡萄膜炎(一种 HTLV-I 血清阳性患者的特发性葡萄膜炎)的临床特征进行了分析。共有 61 例 HTLV-I 葡萄膜炎患者(25 名男性和 31 名女性)参与了此次分析。中度至重度玻璃体混浊伴轻度虹膜炎和视网膜血管炎的中间葡萄膜炎是最具特征性的表现,大多数患者(占所有患者的 66%,或 20 至 49 岁成年患者的 84%)均有此表现。57%的患者葡萄膜炎累及单眼,43%累及双眼,起病亚急性,表现为眼前漂浮物和视物模糊。葡萄膜炎对局部或全身使用糖皮质激素治疗反应良好,但许多病例会复发。相当数量的患者(占所有患者的 15%,女性患者的 25%)既往有格雷夫斯病伴甲状腺功能亢进病史。

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