从甲基苯丙胺滥用者尸体采集的血液样本中甲基苯丙胺浓度的部位依赖性。

Site dependence of methamphetamine concentrations in blood samples collected from cadavers of people who had been methamphetamine abusers.

作者信息

Miyazaki T, Kojima T, Yashiki M, Wakamoto H, Iwasaki Y, Taniguchi T

机构信息

Department of Legal Medicine, Hiroshima University School of Medicine, Japan.

出版信息

Am J Forensic Med Pathol. 1993 Jun;14(2):121-4. doi: 10.1097/00000433-199306000-00003.

DOI:10.1097/00000433-199306000-00003

PMID:8328430

Abstract

Various blood samples were collected from heart cavities and blood vessels in eight autopsy cases of people who had been methamphetamine abusers. Methamphetamine and its metabolite, amphetamine, were determined by gas chromatography-mass spectrometry-selected ion monitoring. In four cases where left and right heart blood samples were collected, methamphetamine concentrations in the left heart blood samples were 1.9-2.6 times higher than those in the right heart blood samples. In three cases where pulmonary vein blood samples were collected, methamphetamine concentrations in the pulmonary vein blood samples were higher than those in other blood samples sites. To interpret the blood methamphetamine concentrations, site dependence should be taken into consideration.

摘要

从八例甲基苯丙胺滥用者的尸检病例中采集了心脏腔室和血管中的各种血液样本。通过气相色谱-质谱选择离子监测法测定甲基苯丙胺及其代谢物苯丙胺。在四例采集了左右心血液样本的病例中，左心血液样本中的甲基苯丙胺浓度比右心血液样本中的高1.9至2.6倍。在三例采集了肺静脉血液样本的病例中，肺静脉血液样本中的甲基苯丙胺浓度高于其他血液样本部位。为了解释血液中甲基苯丙胺的浓度，应考虑部位依赖性。