Acute lymphoidic leukemia in a patient with thrombocytopenia/absent radii (Tar) syndrome.

PURPOSE

Patients with thrombocytopenia, absent radii (TAR) syndrome have a spontaneous amelioration of thrombocytopenia after infancy. No individual with the syndrome has been reported to develop subsequent bone marrow disease.

PATIENTS AND METHODS

We report a child with TAR syndrome who developed acute lymphoidic leukemia.

RESULTS AND CONCLUSIONS

The TAR syndrome may predispose patients to other forms of marrow disease (as do other inherited marrow failure diseases). Additional cases are needed to confirm this hypothesis.