Yörükoğlu Y, Ilgit E, Zengin M, Nazliel K, Salman E, Yucel E
Department of Cardiovascular Surgery, Gazi University, Medical School, Ankara, Turkey.
Angiology. 1993 Jul;44(7):527-32. doi: 10.1177/000331979304400704.
Thromboangiitis obliterans (TAO) is an occlusive vascular disease traditionally known to be almost exclusive to young male smokers. The disease was considered to be extremely rare in women, seen only as isolated, novel case reports in the literature. In the past decade, however, a dramatic increase in the incidence of female TAO has been observed. In this paper the authors report 7 cases of clinically and angiographically verified female TAO. The world literature in regard to the diagnostic criteria, changing incidence, and etiology is reviewed. They conclude that the increased use of tobacco among young women in the past two to three decades is responsible for this dramatic change.
血栓闭塞性脉管炎（TAO）是一种闭塞性血管疾病，传统上认为几乎仅见于年轻男性吸烟者。该疾病在女性中被认为极为罕见，在文献中仅作为孤立的新病例报告出现。然而，在过去十年中，女性TAO的发病率显著增加。在本文中，作者报告了7例经临床和血管造影证实的女性TAO病例。并对世界文献中关于诊断标准、发病率变化和病因进行了综述。他们得出结论，过去二三十年年轻女性烟草使用的增加是造成这一显著变化的原因。
