根据国际抗癌联盟（UICC）分期分类和日本胃癌研究学会的《胃癌研究总则》对胃癌患者术后生存曲线进行比较。

Comparison of survival curves of gastric cancer patients after surgery according to the UICC stage classification and the General Rules for Gastric Cancer Study by the Japanese Research Society for gastric cancer.

作者信息

Nio Y, Tsubono M, Kawabata K, Masai Y, Hayashi H, Meyer C, Inoue K, Tobe T

机构信息

First Department of Surgery, Kyoto University Faculty of Medicine, Japan.

出版信息

Ann Surg. 1993 Jul;218(1):47-53. doi: 10.1097/00000658-199307000-00008.

DOI:10.1097/00000658-199307000-00008

PMID:8328829

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1242899/

Abstract

OBJECTIVE

This study compared the UICC classification with the General Rules for Gastric Cancer Study (GRGCS) of the Japanese Research Society by analyzing recent results of gastric cancer surgery in Japan.

SUMMARY BACKGROUND DATA

The present UICC stage classification for gastric cancer was published in 1987 and the Japanese GRGCS were published in 1985. Both are based on the results of surveys conducted in the early 1970s.

METHODS

The survival curves of 926 patients, who underwent gastric cancer surgery between 1982 and 1985 at Kyoto University Hospital and its 31 associated hospitals, were analyzed according to the UICC classification and the GRGCS using SAS computer software.

RESULTS

There was no difference in survival rate between UICC stages IA and IB. GRGCS stage III was found to include UICC stages II, IIIA, and IIIB, and GRGCS stage IV included UICC stages IIIA, IIIB, and IV, with significantly different survival rates. In contrast, each UICC stage included different GRGCS stages with no significant differences in survival rates. The survival rate of stage IV patients of both classifications who underwent gastrectomy was significantly higher than that of stage IV patients receiving bypass or exploratory surgeries.

CONCLUSIONS

The UICC classification is better than the GRGCS for classifying gastric cancer in Japan. However, UICC stage I does not need to be subdivided into stages IA and IB, and stage IV should be further subdivided into stages IVA and IVB according to the surgery performed: IVA, gastrectomy, and IVB, bypass or exploratory surgery.

摘要

目的

本研究通过分析日本近期胃癌手术结果，比较国际抗癌联盟（UICC）分类与日本胃癌研究学会的《胃癌研究总则》（GRGCS）。

总结背景数据

目前的UICC胃癌分期分类于1987年发布，日本的GRGCS于1985年发布。两者均基于20世纪70年代初进行的调查结果。

方法

使用SAS计算机软件，根据UICC分类和GRGCS对1982年至1985年在京都大学医院及其31家关联医院接受胃癌手术的926例患者的生存曲线进行分析。

结果

UICC IA期和IB期的生存率无差异。发现GRGCS III期包括UICC II期、IIIA期和IIIB期，GRGCS IV期包括UICC IIIA期、IIIB期和IV期，生存率有显著差异。相反，每个UICC期包括不同的GRGCS期，生存率无显著差异。接受胃切除术的两种分类IV期患者的生存率显著高于接受旁路手术或探查手术的IV期患者。