Ariza J, Pujol M, Valverde J, Nolla J M, Rufí G, Viladrich P F, Corredoira J M, Gudiol F
Infectious Disease Service, Hospital de Bellvitge, Universidad de Barcelona, Spain.
Clin Infect Dis. 1993 Jun;16(6):761-5. doi: 10.1093/clind/16.6.761.
Between 1974 and 1989 we prospectively observed 530 patients with brucellosis. The findings for 62 patients (42 males and 20 females; mean age, 34.7 years) with 63 episodes in which the sacroiliac joint was involved (the most frequent osteoarticular location [11.7%]) were analyzed. Ten of the older patients (mean age, 55.3 years) had concomitant spondylitis. Systemic symptoms were usually important, and characteristic pain and findings of sacroiliitis were observed in approximately 75% of cases. Blood cultures were positive for Brucella melitensis for 44 patients. The most frequent radiographic findings were blurring of articular margins (42 cases) and widening of the sacroiliac space (20 cases). No radiographic anomalies were detected in 13 cases. Results of 99mTc and gallium-67 bone scans were abnormal in approximately 90% of cases (abnormalities were often mild). Overall, clinical, radiographic, and isotopic bone scan findings were sensitive and useful, although they were occasionally minimal or difficult to evaluate, making diagnostic findings confusing or misleading. Brucellar sacroiliitis is a mild disease associated with a good outcome similar to that observed for patients with uncomplicated brucellosis.
1974年至1989年间,我们对530例布鲁氏菌病患者进行了前瞻性观察。分析了62例患者(42例男性和20例女性;平均年龄34.7岁)共63次累及骶髂关节的情况(最常见的骨关节部位[11.7%])。10例老年患者(平均年龄55.3岁)合并脊柱炎。全身症状通常较为明显,约75%的病例观察到骶髂关节炎的典型疼痛和表现。44例患者的血培养布鲁氏菌羊种呈阳性。最常见的影像学表现为关节边缘模糊(42例)和骶髂间隙增宽(20例)。13例未检测到影像学异常。约90%的病例99mTc和镓-67骨扫描结果异常(异常通常较轻)。总体而言,临床、影像学和同位素骨扫描结果敏感且有用,尽管偶尔表现轻微或难以评估,导致诊断结果混淆或产生误导。布鲁氏菌性骶髂关节炎是一种轻度疾病,预后良好,与无并发症的布鲁氏菌病患者相似。