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特发性腹膜后纤维化

Idiopathic retroperitoneal fibrosis.

作者信息

Keith D S, Larson T S

机构信息

Mayo Graduate School of Medicine, Mayo Clinic and Foundation, Rochester, MN 55905.

出版信息

J Am Soc Nephrol. 1993 May;3(11):1748-52. doi: 10.1681/ASN.V3111748.

Abstract

Herein is described a case report of urinary tract obstruction due to idiopathic retroperitoneal fibrosis (IRF) in a 43-year-old man. Recent studies suggest that IRF fits into the broader pathologic heading of chronic periaortitis. Although there may be more than one pathophysiologic mechanism, growing evidence suggests that many cases of IRF are due to an autoallergic reaction to lipid material in the atheromatous aorta. Computed tomographic scanning has supplanted excretory and retrograde urography in the diagnosis of this condition. Ureterolysis and steroids remain the mainstays in the treatment of IRF. Even after successful decompression of urinary obstruction, long-term follow-up is required in these patients because of the possibility of other complications such as vena caval or duodenal obstruction.

摘要

本文描述了一例43岁男性因特发性腹膜后纤维化(IRF)导致尿路梗阻的病例报告。最近的研究表明,IRF属于慢性主动脉周炎这一更广泛的病理范畴。虽然可能存在多种病理生理机制,但越来越多的证据表明,许多IRF病例是由于对动脉粥样硬化主动脉中的脂质物质产生自身过敏反应所致。计算机断层扫描已取代排泄性和逆行性尿路造影用于该疾病的诊断。输尿管松解术和类固醇仍然是IRF治疗的主要方法。即使尿路梗阻成功解除,由于这些患者可能出现其他并发症,如腔静脉或十二指肠梗阻,仍需要长期随访。

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