Jawed S H, Krishnan V H, Prasher V P, Corbett J A
Weston Hospital, Leamington Spa, Warwickshire.
Br J Psychiatry. 1993 Jun;162:835-7. doi: 10.1192/bjp.162.6.835.
The case of a person with severe mental handicap whose pica became uncontrollable during episodes of depressive illness is described. Treatment of the depression with lofepramine markedly reduced the pica, and withdrawal of lofepramine led to recurrence. It is suggested that biological symptoms of depression should be monitored in people with severe mental handicap who show significant episodic worsening of long-standing repetitive behaviour.
本文描述了一名重度智力障碍患者的病例，该患者在抑郁症发作期间异食癖变得无法控制。用洛非帕明治疗抑郁症显著减轻了异食癖，停用洛非帕明导致复发。建议对长期存在重复行为且有明显发作性恶化的重度智力障碍患者监测抑郁症的生物学症状。
