Kyösola K
Histochemistry. 1977 Feb 1;50(4):337-46. doi: 10.1007/BF00507127.
Cholinesterase histochemistry of the human gall bladder was studied using two specific methods. Distribution of acetylcholinesterase: In the mucosa, nerve fascicles consisting of densely packed parallel single nerve fibres, small ganglia and "spot"- and "glomerule"- like concentrations of acetylcholinesterase activity were observed. In the muscle layer, a wide-meshed network of delicate nerves, with occational areas of very dense innervation, and small ganglia were seen. In the serosa, "glomerule"- like structures surrounded by dense "baskets" of delicate nerves were observed.-- The general scheme of distribution of non-specific cholinesterases was similar to that of acetylcholinesterase. It seems that the cholinergic innervation of the gall bladder is related to both secretion and absorption and contractility. Some cholinergic nerves are probably sensory, especially because acetylcholinesterase-positive structures, possibly pressure of stretch receptors, supplied with nerves were observed in the mucosa and the serosa. The cholinergic innervation of the gall bladder muscle was scarce except occasional areas of very dense innervation. It may thus be concluded that the intermuscle spread of excitation plays an important role, the majority of the smooth muscle cells receiving their nervous influence via electrotonic coupling.
采用两种特定方法对人胆囊进行胆碱酯酶组织化学研究。乙酰胆碱酯酶的分布：在黏膜中，观察到由紧密排列的平行单神经纤维、小神经节以及乙酰胆碱酯酶活性呈“点状”和“小球状”聚集组成的神经束。在肌层中，可见由纤细神经构成的宽网眼网络，有偶尔神经支配非常密集的区域以及小神经节。在浆膜中，观察到被纤细神经密集“篮状”结构包围的“小球状”结构。——非特异性胆碱酯酶的总体分布模式与乙酰胆碱酯酶相似。胆囊的胆碱能神经支配似乎与分泌、吸收及收缩性均有关。一些胆碱能神经可能是感觉神经，尤其是因为在黏膜和浆膜中观察到了乙酰胆碱酯酶阳性结构，可能是有神经支配的牵张感受器压力结构。除了偶尔神经支配非常密集的区域外，胆囊肌层的胆碱能神经支配稀少。因此可以得出结论，兴奋在肌间的传播起重要作用，大多数平滑肌细胞通过电紧张性耦联接受神经影响。
