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一种使用植入式传感器测量动脉顺应性的新装置。描述及首次实验应用。

A new device for the measurement of the arterial compliance using implantable sensors. Description and first experimental application.

作者信息

Welz A, Murrmann G, Hammer C, Stegner U

机构信息

Department of Cardiac Surgery, University of Ulm, FRG.

出版信息

Eur Surg Res. 1993;25(4):245-53. doi: 10.1159/000129284.

Abstract

To determine the compliance of experimental arterial grafts and its chronic adaptation after implantation, a new device for measurements was developed which is combined with implantable sensors. The system is based on the physical induction phenomenon. Each sensor comprises two small coils of copper wire which are sutured opposite to each other to the arterial vessel. Up to 3 sensors are adapted to one electrical connector which can be covered subcutaneously. The device is able to read pulsatile diameter excursions of arterial vessels down to 0.02 mm. It was applied first to evaluate the elastic properties of a 4-mm dialdehyde-starch-preserved bovine internal mammary artery implanted in the canine femoral artery position. For comparison an ePTFE graft was used. At implantation the compliance of the biograft was calculated to be 0.028 +/- 0.009% mm Hg-1, which was half of the compliance of the native femoral artery (0.06 +/- 0.0025% mm Hg-1), but superior if compared to the PTFE (0.008 +/- 0.005% mm Hg-1). Within 6 months the compliance of the femoral artery decreased to 0.039 +/- 0.013% mm Hg-1, which was well matched now to the compliance of the biograft (0.027 +/- 0.005% mm Hg-1).

摘要

为了确定实验性动脉移植物的顺应性及其植入后的慢性适应性,开发了一种与植入式传感器相结合的新型测量装置。该系统基于物理感应现象。每个传感器包括两个相互相对缝合到动脉血管上的小铜线圈。一个电连接器可适配多达3个传感器,该电连接器可皮下覆盖。该装置能够读取低至0.02毫米的动脉血管搏动直径变化。它首先被用于评估植入犬股动脉位置的4毫米二醛淀粉保存的牛乳内动脉的弹性特性。作为对照,使用了ePTFE移植物。植入时,生物移植物的顺应性计算为0.028±0.009% mmHg-1,这是天然股动脉顺应性(0.06±0.0025% mmHg-1)的一半,但与PTFE(0.008±0.005% mmHg-1)相比更好。在6个月内,股动脉的顺应性降至0.039±0.013% mmHg-1,此时与生物移植物的顺应性(0.027±0.005% mmHg-1)非常匹配。

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