McNally M A, Mollan R A
Department of Orthopaedic Surgery, Queen's University of Belfast, Musgrave Park Hospital, Northern Ireland.
J Bone Joint Surg Br. 1993 Jul;75(4):640-4. doi: 10.1302/0301-620X.75B4.8331123.
The effect of Charnley cemented total hip replacement on venous blood flow in the legs and its relationship to deep-vein thrombosis were investigated in 413 patients. Blood flow was measured using strain-gauge plethysmography before operation, after surgery, and after discharge from hospital. There was a significant reduction in both venous capacitance and venous outflow, affecting both legs but greater in the operated leg. Venous flow remained significantly below preoperative levels in the operated leg six weeks after surgery. There was a highly significant correlation between the degree of reduction in blood flow and the development of postoperative deep-vein thrombosis. Venous stasis was shown to be a major factor in venous thrombogenesis.
对413例患者研究了Charnley骨水泥型全髋关节置换术对腿部静脉血流的影响及其与深静脉血栓形成的关系。分别于术前、术后及出院后采用应变计体积描记法测量血流。静脉容量和静脉流出量均显著减少，双腿均受影响，但手术侧腿更明显。术后六周，手术侧腿的静脉血流仍显著低于术前水平。血流减少程度与术后深静脉血栓形成的发生之间存在高度显著的相关性。静脉淤滞被证明是静脉血栓形成的主要因素。
