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[鹦鹉热衣原体和肺炎支原体所致肺炎患者支气管肺泡灌洗液体细胞群的研究]

[Study of cell populations of bronchoalveolar lavage fluid in patients with pneumonia due to Chlamydia psittaci and Mycoplasma pneumoniae].

作者信息

Hayashi Y, Asano T, Ito G, Yamada Y, Matsuura T, Adachi S, Yamamoto K, Nakamura A, Takeyama S, Takeuchi T

机构信息

Department of Respiratory Diseases, Kasugai Municipal Hospital, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1993 May;31(5):569-74.

PMID:8331841
Abstract

We have performed bronchoalveolar lavage (BAL) examination in 27 cases; 5 with Chlamydial pneumonia, 7 with Mycoplasmal pneumonia and 15 in the control group (5 non-smokers, 10 smokers), and the following results were obtained. 1. In Chlamydial pneumonia and Mycoplasmal pneumonia, the cell population of alveolar macrophages in BALF decreased (p < 0.01) and that of lymphocytes increased compared with control group (p < 0.01). 2. In all cases of Mycoplasmal pneumonia without peripheral eosinophilia, the cell population of eosinophils in BALF increased compared with cases of Chlamydial pneumonia (p < 0.05). These results indicate that lymphocytes played the main role in the immune host defense in Chlamydial pneumonia, whereas infiltration of lymphocytes and eosinophils into the pneumonic lesion occurred in Mycoplasma pneumoniae infection.

摘要

我们对27例患者进行了支气管肺泡灌洗(BAL)检查;其中5例为衣原体肺炎,7例为支原体肺炎,15例为对照组(5例非吸烟者,10例吸烟者),并得到了以下结果。1. 与对照组相比,衣原体肺炎和支原体肺炎患者的支气管肺泡灌洗液(BALF)中肺泡巨噬细胞数量减少(p < 0.01),淋巴细胞数量增加(p < 0.01)。2. 在所有无外周血嗜酸性粒细胞增多的支原体肺炎病例中,BALF中嗜酸性粒细胞数量比衣原体肺炎病例增加(p < 0.05)。这些结果表明,淋巴细胞在衣原体肺炎的免疫宿主防御中起主要作用,而在肺炎支原体感染中,淋巴细胞和嗜酸性粒细胞浸润到肺部病变中。

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