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[核医学在疲劳骨折综合诊断中的应用]

[Nuclear medicine in the integrated diagnosis of fatigue fractures].

作者信息

Piffanelli A, Giganti M, Cittanti C, Colamussi P

机构信息

Cattedra di Medicina Nucleare, Istituto di Radiologia dell'Università di Ferrara.

出版信息

Radiol Med. 1993 May;85(5 Suppl 1):272-5.

PMID:8332807
Abstract

Nuclear medicine applications deal with the functional and dynamic study of organs and apparatuses in each diagnostic protocol. Bone scintigraphy (diagnostic accuracy: 80%) plays an important role in the differential diagnosis of the various musculoskeletal conditions in sports, mainly in the so-called "stress syndrome". The method is rather simple, including three steps: 1) study of radioactivity in the ROI; 2) capillary phase, with early imaging; 3) bone phase, with a static image 5 hours after injection. Slight differences in marker uptake, with fusiform and elongated marker accumulation areas, can be seen in the tibial stress syndrome, which exhibits no increase in the vascular phase, while in stress fractures, mainly in the late stages, increased activity can be seen in the arteriolar and capillary phases. Stress fractures are divided into 5 stages, from stage 1 = < 20% skeletal involvement to stage 5 = complete fracture, with > 80% bone involvement. The advantages of 3-phase bone scintigraphy can be summarized as follows: 1) it yields objective information, where clinics and radiology are often negative; 2) it allows the differential diagnosis between soft tissue lesions and bone fractures even in an early stage; 3) it allows prognosis to be made and the resumption of sport activity to be planned.

摘要

核医学应用涉及每个诊断方案中器官和设备的功能及动态研究。骨闪烁显像(诊断准确率:80%)在运动中各种肌肉骨骼疾病的鉴别诊断中发挥着重要作用,主要用于所谓的“应力综合征”。该方法相当简单,包括三个步骤:1)研究感兴趣区域(ROI)的放射性;2)毛细血管期,进行早期成像;3)骨期,在注射后5小时进行静态成像。在胫骨应力综合征中可见标记物摄取略有差异,标记物积聚区域呈梭形且拉长,血管期无增加,而在应力性骨折中,主要在后期,小动脉和毛细血管期可见活性增加。应力性骨折分为5个阶段,从第1阶段 = 骨骼受累 < 20%到第5阶段 = 完全骨折,骨骼受累 > 80%。三相骨闪烁显像的优点可总结如下:1)它能提供客观信息,而临床和放射学检查往往呈阴性;2)即使在早期也能对软组织病变和骨折进行鉴别诊断;3)它有助于进行预后评估并规划恢复体育活动。

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