Bothe H W, Lee S W, Samii M
Neurosurgical Clinic, Nordstadt Hospital, Medical School, Hannover, Federal Republic of Germany.
Acta Neurochir (Wien). 1993;122(1-2):105-12. doi: 10.1007/BF01446995.
Somatosensory evoked potentials (SEP) and intracranial pressure (ICP) were studied in cats, suffering from a chronic space-occupying lesion produced by enlargement of an epidural balloon over the left sensomotory cortex. Our study shows that latency alterations of SEP are not dependent on the degree of ICP. Additionally, the results obtained demonstrate that chronic space-occupying lesions cause continuous prolongation of SEP latencies, probably produced by atrophy of the compressed tissue. Regarding the clinical importance of SEP measurements, we concluded that they are not suitable for estimating the degree of ICP. However, they are useful to evaluate tissue damage caused by mass effects in the acute and chronic phase of various space-occupying processes.
在猫身上研究了体感诱发电位（SEP）和颅内压（ICP），这些猫患有由左感觉运动皮层上方硬膜外球囊扩张产生的慢性占位性病变。我们的研究表明，SEP潜伏期的改变不依赖于ICP的程度。此外，所获得的结果表明，慢性占位性病变会导致SEP潜伏期持续延长，这可能是由受压组织萎缩所致。关于SEP测量的临床重要性，我们得出结论，它们不适合用于估计ICP的程度。然而，它们对于评估各种占位性病变过程的急性期和慢性期由占位效应引起的组织损伤是有用的。
