高剂量他莫昔芬治疗复发性高级别胶质瘤：临床稳定和肿瘤消退的报告
High dose tamoxifen in the treatment of recurrent high grade glioma: a report of clinical stabilization and tumour regression.
作者信息
Baltuch G, Shenouda G, Langleben A, Villemure J G
机构信息
Department of Neurology and Neurosurgery, McGill University, Montreal.
出版信息
Can J Neurol Sci. 1993 May;20(2):168-70. doi: 10.1017/s0317167100047788.
PMID:8334583
Abstract
We present a case of recurrent glioma, previously treated with maximal surgery and radiation in which a high dose of tamoxifen has stabilized the tumour clinically and has resulted in it's radiologic regression. Given tamoxifen's relative lack of toxicity, it might serve as a useful adjuvant in the treatment of recurrent glioma.
摘要
我们报告一例复发性胶质瘤病例，该患者先前已接受了最大限度的手术和放疗，大剂量他莫昔芬治疗使肿瘤在临床上得以稳定，并使其出现影像学退缩。鉴于他莫昔芬相对较低的毒性，它可能作为复发性胶质瘤治疗中一种有用的辅助药物。
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