Smith S J, Harding A E
Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, London, UK.
J Neurol. 1993 Jun;240(6):367-72. doi: 10.1007/BF00839969.
Electroencephalograms (EEGs) and evoked potentials (EPs) were studied in 43 patients with mitochondrial myopathies. Abnormalities were found most frequently in patients who presented predominantly or exclusively with central nervous system (CNS) dysfunction (abnormal EEGs in 18 of 21 patients, abnormal EPs in 9 of 11 patients). However, of patients presenting with ocular myopathy or proximal muscle weakness who had little or no CNS involvement clinically, 8 of 22 had abnormal EEGs and 5 of 10 had abnormal EPs, suggesting that electrophysiological tests are of value in demonstrating subclinical CNS disease in mitochondrial myopathy, although the abnormalities are not specific.
对43例线粒体肌病患者进行了脑电图（EEG）和诱发电位（EP）研究。在主要或仅表现为中枢神经系统（CNS）功能障碍的患者中，异常情况最为常见（21例患者中有18例脑电图异常，11例患者中有9例诱发电位异常）。然而，在临床上很少或没有中枢神经系统受累的眼肌病或近端肌无力患者中，22例中有8例脑电图异常，10例中有5例诱发电位异常，这表明电生理检查在显示线粒体肌病的亚临床中枢神经系统疾病方面具有价值，尽管这些异常并不具有特异性。
